Bovine respiratory disease in Brasil: a short review

Mariana Motta Castro, Thalita Evani Silva de Oliveira, Selwyn Arligton Headley


The bovine respiratory disease (BRD) complex is a multifactorial and multietiological disease entity described in all geographic regions of Brazil. This brief review discusses aspects related to epidemiology, etiologic agents, clinical and pathological manifestations, and challenges in the diagnosis of BRD in Brazil. The main infectious disease agents associated with respiratory outbreaks in cattle from Brazil are bovine alphaherpesvirus type 1, bovine viral diarrhea virus, bovine respiratory syncytial virus, and Mycoplasma bovis. Ovine gammaherpesvirus-2 and HoBi-like pestivirus have been associated with the development of pneumonia in adult cattle and calves, respectively in Brazil, and should be considered as possible causes of BRD. Additionally, studies using epidemiological data, histopathological and molecular associations with morbidity and mortality should be carried out in Brazil, to demonstrate the real impacts of BRD on livestock.


Epidemiology; Cattle disease; Diagnosis; Respiratory pathogens.

Full Text:



Andrews, G. A., & Kennedy, G. A. (1997). Respiratory diagnostic pathology. The Veterinary Clinics of North America. Food Animal Practice, 13(3), 515-547. doi: 10.1016/s0749-0720(15)30312-1

Apley, M. (2006). Bovine respiratory disease: pathogenesis, clinical signs, and treatment in lightweight calves. The Veterinary Clinics of North America. Food Animal Practice, 22(2), 399-411. doi: 10.1016/j. cvfa.2006.03.009

Baptista, A. L., Rezende, A. L., Fonseca, P. A., Nogueira, G. M., Headley, S. A., Menezes, G. L., Alfieri, A. A., & Saut, J. P. E. (2017). Bovine respiratory disease complex associated mortality and morbidity rates in feedlot cattle from southeastern Brazil. Journal of Infection in Developing Countries, 11(10), 791-799. doi: 10.3855/jidc.9296

Bauermann, F. V., Ridpath, J. F., Weiblen, R., & Flores, E. F. (2013). HoBi-like viruses: an emerging group of pestiviruses. Journal of Veterinary Diagnostic Investigation, 25(1), 6-15. doi: 10.1177/10406387124 73103

Beuttemmuller, E. A., Alfieri, A. F., Headley, S. A., & Alfieri, A. A. (2017). Brazilian strain of bovine respiratory coronavirus is derived from dual enteric and respiratory tropism. Genetics and Molecular Research, 16(2), gmr16029580. doi: 10.4238/gmr16029580

Blakebrough-Hall, C., McMeniman, J. P., & González, L. A. (2020). An evaluation of the economic effects of bovine respiratory disease on animal performance, carcass traits, and economic outcomes in feedlot cattle defined using four BRD diagnosis methods. Journal of Animal Science, 98(2), 1-11. doi: 10.10 93/jas/skaa005

Booker, C. W., Abutarbush, S. M., Morley, P. S., Jim, G. K., Pittman, T. J., Schunicht, O. C.,…Janzen, E. D. (2008). Microbiological and histopathological findings in cases of fatal bovine respiratory disease of feedlot cattle in Western Canada. Canadian Veterinary Journal, 49(5), 473-481. Retrieved from articles/PMC2359492/pdf/ cvj49pg473.pdf

Brasil, N. D. A., Hinnah, F. L., Fiss, L., Sallis, E. S. V., Grecco, F. B., Ladeira, S. R. L., Marcolongo-Pereira, C., & Schild, A. L. (2013). Doenças respiratórias em bezerros na região sul do Rio Grande do Sul: estudo retrospectivo de 33 surtos. Pesquisa Veterinária Brasileira, 33(6), 745-751. doi: 10.1590/S0100-736X2013000600010

Caswell, J. L., & Archambault, M. (2007). Mycoplasma bovis pneumonia in cattle. Animal Health Research Reviews, 8(2), 161-186. doi: 10.1017/s1466252307001351


Semina: Ciênc. Agrár.
Londrina - PR
E-ISSN 1679-0359
DOI: 10.5433/1679-0359
Este obra está licenciado com uma Licença Creative Commons Atribuição-NãoComercial 4.0 Internacional