Pemphigus foliaceus in a sheep

Autores

  • Aline Antas Cordeiro Cavalcanti Universidade Federal de Campina Grande
  • Ana Claudia Campos Universidade Federal de Sergipe
  • Aline Guedes Mamede Moraes Universidade Federal de Campina Grande
  • Clarice Ricardo de Macêdo Pessoa Universidade Federal de Sergipe
  • Franklin Riet-Correa Universidade Federal de Campina Grande
  • Marcia Almeida Melo Universidade Federal de Campina Grande,
  • Edisio Oliveira Azevedo Universidade Federal de Sergipe

DOI:

https://doi.org/10.5433/1679-0359.2019v40n2p1001

Palavras-chave:

Pemphigus foliaceus, Sheep, Skin.

Resumo

Pemphigus foliaceus (PF) is an autoimmune disease of the skin and is the most common form of pemphigus in domestic animals. This work reports a case of pemphigus foliaceus in a Santa Inês hair sheep. The ewe presented with multifocal bilateral crusted alopecic dermatitis affecting the chest, abdomen, and pelvic and thoracic limbs. Parakeratotic hyperkeratosis and acanthosis, in addition to ballooning degeneration of keratinocytes and subcorneal pustules, were observed histologically, and acantholytic cells and neutrophils were observed within the pustules. In the superficial and deep dermal tissues, there was intense eosinophilic infiltration and the presence of rare macrophages. These microscopic findings were characteristic of PF, and treatment with dexamethasone was ineffective. This disease is rare in sheep, and this is the first case report to be published in Brazil.

Métricas

Carregando Métricas ...

Biografia do Autor

Aline Antas Cordeiro Cavalcanti, Universidade Federal de Campina Grande

Discente de Doutorado, Programa de Pós-Graduação em Medicina Veterinária

Ana Claudia Campos, Universidade Federal de Sergipe

Profa., Dra., Departamento de Medicina Veterinária

Aline Guedes Mamede Moraes, Universidade Federal de Campina Grande

MSc., Médica Veterinária

Clarice Ricardo de Macêdo Pessoa, Universidade Federal de Sergipe

Profa., Dra., Departamento de Medicina Veterinária

Franklin Riet-Correa, Universidade Federal de Campina Grande

Prof., Dr., Departamento de Medicina Veterinária

Marcia Almeida Melo, Universidade Federal de Campina Grande,

Profa., Dra., Departamento de Medicina Veterinária

Edisio Oliveira Azevedo, Universidade Federal de Sergipe

Prof., Dr., Departamento de Medicina Veterinária

Referências

BRENNER, D. J.; STOKKING, L.; DONOVAN, T. A.; LAMBERSKI, N. Pemphigus foliaceus in a barbary sheep (Ammotragus lervia). Veterinary Record, London, v. 17, n. 165, p. 509-510, 2009.

KOLOU, L.; KUSUMI, A.; STEINBERG, M. S.; KLAUS-KOVTUN, V.; STANLEY, J. R. Human autoantibodies against a desmosomal core protein in pemphigus foliaceus. Journal of Experimental Medicine, New York, v. 160, n. 5, p. 1509-1518, 1984.

LAMBACHER, B.; SCHOISWOHL, J.; BRUNTHALER, R.; WITTEK, T.; KRAMETTER-FRÖTSCHER, R. Successful treatment of pemphigus foliaceus in a Berrichon du Cher ram with methylprednisolone acetate. Veterinary Dermatology, Oxford, v. 28, n. 5, p. 499-e117, 2017.

OLIVRY, T.; LAVOY, A.; DUNSTON, S. M.; BROWN, R. S.; LENNON, E. M.; WARREN, S. J.; PRISAYANH, P.; MÜLLER, E. J.; SUTER, M. M.; DEAN, G. A. Desmoglein-1 is a minor autoantigen in dogs with pemphigus foliaceus. Veterinary Immunology and Immunopathology, Amsterdam, v. 110, n. 3-4, p. 245-255, 2006.

PAPPALARDO, E.; ABRAMO, F.; NOLI, C. Pemphigus foliaceus in a goat. Veterinary Dermatology, Oxford, v. 13, n. 6, p. 331-336, 2002.

SCHMIDT, E.; ZILLIKENS, D. Modern diagnosis of autoimmune blistering skin diseases. Autoimmunity Reviews, Amsterdam, v. 10, n. 2, p. 84-89, 2010.

SCOTT, D. W.; MANNING, T. O.; SMITH, C. A.; LEWIS, R. M. Pemphigus and pemphigoid in dogs, cats and horses. Annals of the New York Academy of Science, New York, v. 420, n. 1, p. 353-360, 1983.

SCOTT, D. W.; SMITH, M. C.; SMITH, C. A.; LEWIS, R. M. Pemphigus foliaceus in a goat. Agri-Practice, Santa Barbara, v. 5, n. 4, p. 38-45, 1984.

VALDEZ, R. A.; GELBERG, H. B.; MORIN, D. E.; ZUCKERMANN, F. A. Use of corticosteroids and aurothioglucose in a pygmy goat with pemphigus foliaceus. Journal of the American Veterinary Medical Association, New York, v. 207, n. 6, p. 761-765, 1995.

VANDENABEELE, S. I. J.; WHITE, S. D.; AFFOLTER, V. K.; KASS, P. H.; IHRKE, P. J. Pemphigus foliaceus in the horse: a retrospective study of 20 cases. Veterinary Dermatology, Oxford, v. 15, n. 6, p. 381-388, 2004.

VAUGHAN, D. F.; CLAY HODGIN, E.; HOSGOOD, G. L.; BERNSTEIN, J. A. Clinical and histopathological features of pemphigus foliaceus with and without eosinophilic in?ltrates: a retrospective evaluation of 40 dogs. Veterinary Dermatology, Oxford, v. 21, n. 2, p. 166-174, 2010.

Downloads

Publicado

2019-04-15

Como Citar

Cavalcanti, A. A. C., Campos, A. C., Moraes, A. G. M., Pessoa, C. R. de M., Riet-Correa, F., Melo, M. A., & Azevedo, E. O. (2019). Pemphigus foliaceus in a sheep. Semina: Ciências Agrárias, 40(2), 1001–1004. https://doi.org/10.5433/1679-0359.2019v40n2p1001

Edição

Seção

Relatos de Casos

Artigos mais lidos pelo mesmo(s) autor(es)