Experimental toxoplasmosis in pregnant rabbits

Jair Rodini Engracia Filho, Julieta Rodini Engrácia de Moraes, Flávio Ruas de Moraes, Daniela Myasaka, Karina Castagnolli, Alvimar José da Costa


The clinical, hematological, obstetrical, immunological and pathological aspects of the experimental toxoplasmosis were investigated in pregnant rabbits orally inoculated with Toxoplasma gondii oocysts. Pregnant rabbits showed to be highly sensible to the toxoplasmic infection. Abortion and death occurred in 100% of the inoculated rabbits. Fever peak was observed between 4o and 9o day pos-infection. Blood parameter showed alterations. Because the hyperacute character presented by the toxoplasmic infection, the humoral immune response was weak. The microscopic and macroscopic exams demonstrated, mainly, alterations in liver, kidney and lungs. These results suggested that pregnant rabbits, orally infected with oocysts of T. gondii are extremely susceptible to this parasite, showing severe alterations in several organs, as well as premature abortion and death.


Toxoplasma gondii; Pregnant rabbits, Abortion.

DOI: http://dx.doi.org/10.5433/1679-0359.2001v22n1p3

Semina: Ciênc. Agrár.
Londrina - PR
E-ISSN 1679-0359
DOI: 10.5433 / 1679-0359
E-mail:  semina.agrarias@uel.br
Este obra está licenciado com uma Licença  Creative Commons Atribuição-NãoComercial 4.0 Internacional