Efect of verminosis on goat immune response

Marilene Machado Silva, Sebastião Pereira de Faria Junior, Maria de Fátima Martins, Patrícia Rabello, Patrícia Maria Pascoal, Heloísa Godoy Bertagnon, Monika Scheibel, Maurício Garcia

Abstract


The purpose of this work was to evaluate the immune response in goats with different degrees of gastrintestinal nematode infection. Ninety adult animals naturally infected were grouped according to the total egg count per feces gram (EPG): group I from zero to 500 EPG, group II from 501 to 2000 and group III above 2000. The parameters studied were serum total protein (STP), evaluated by biuret method; globulin (Glob), calculated by the difference between STP and serum albumin; gammaglobulin (Gglob), estimated throughout electrophoresis; immunoglobulin (Ig), estimated by turbidometry test with ZnSO4 and absolute lymphocyte count (Lymp / ml). It was found statistically decrease in three parameters (STP, Ig and Lymp / ml) for group III. For Glob and Gglob, the decrease found was not statistically significant. These results show a depressor effect of nematode infection on humoral immune system. The intense dispersion of Glob and Gglob data can explain the not significant decrease found in those parameters. It was concluded that goats with intense nematode infection (above 2000 EPG) can show immunedepression, with impairment of lymphocyte count and serum antibody level.


Keywords


Caprine; Verminosis; Immunossupression.



DOI: http://dx.doi.org/10.5433/1679-0359.2002v23n1p15

Semina: Ciênc. Agrár.
Londrina - PR
E-ISSN 1679-0359
DOI: 10.5433/1679-0359
E-mail: semina.agrarias@uel.br
Este obra está licenciado com uma Licença Creative Commons Atribuição-NãoComercial 4.0 Internacional