Histopathological and molecular diagnosis of Mycoplasma sp. infection in rats kept in a conventional animal facility

Rosangela Boeck, Ronei Saldanha Lopes, Jane Silveira Fraga, Sandra Fernandez, Fernando Rosado Spilki


The chronic infection by Mycoplasma pulmonis is frequently found in rats  kept in conventional premises and may influence the results of  the experiments conducted using these animals. During the clinical presentation of the infection animals develop among other manifestations clinical signs of respiratory system impairment. On the present study, we report the diagnosis the histopathological and molecular diagnosis of Mycoplasma sp. infection in Wistar rats both presenting clinical signs of infection and health animals kept in the same colony. The efficacy of therapeutic and prophylactic actions is discussed.


Mycoplasma pulmonis; Rats; Diagnosis

DOI: http://dx.doi.org/10.5433/1679-0359.2010v31n4p1045

Semina: Ciênc. Agrár.
Londrina - PR
E-ISSN 1679-0359
DOI: 10.5433/1679-0359
E-mail: semina.agrarias@uel.br
Este obra está licenciado com uma Licença Creative Commons Atribuição-NãoComercial 4.0 Internacional